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Description

An autoimmune disease is a condition arising from an abnormal immune response to a normal body part. There are at least 80 types of autoimmune diseases. Nearly any body part can be involved. Common symptoms include low-grade fever and feeling tired. Often symptoms come and go. The cause is generally unknown. Some autoimmune diseases such as lupus run in families, and certain cases may be triggered by infections or other environmental factors. Some common diseases that are generally considered autoimmune include celiac disease, diabetes mellitus type 1, Graves’ disease, inflammatory bowel disease, multiple sclerosis, psoriasis, rheumatoid arthritis, and systemic lupus erythematosus. The diagnosis can be difficult to determine.

 

Treatment depends on the type and severity of the condition. Non-steroidal anti-inflammatory drugs (NSAIDs) and immuno-suppressants are often used. Intravenous immunoglobulin may also occasionally be used. While treatment usually improves symptoms, they do not typically cure the disease. About 24 million (7%) people in the United States are affected by an autoimmune disease. Women are more commonly affected than men. Often they start during adulthood. The first autoimmune diseases were described in the early 1900s.

For a disease to be regarded as an autoimmune disease it needs to answer to Witebsky’s postulates (first formulated by Ernest Witebsky and colleagues in 1957 and modified in 1994)

  • Direct evidence from the transfer of disease-causing antibody or disease-causing T lymphocyte white blood cells
  • Indirect evidence based on reproduction of the autoimmune disease in experimental animals
  • Circumstantial evidence from clinical clues
  • Genetic evidence suggesting “clustering” with other autoimmune diseases

Scope of Research

An autoimmune disease is a condition arising from an abnormal immune response to a normal body part. There are at least 80 types of autoimmune diseases, out of these we could cover few. Nearly any body part can be involved. Common symptoms include low-grade fever and feeling tired.

Systemic Lupus Erythematosus Reactive Arthritis
Rheumatoid Arthritis Type 1 Diabetes
Sjogren’s Syndrome Myasthenia Gravis
Multiple Sclerosis Immunological Disorder
Hashimoto’s Thyroiditis Pernicious Anaemia
Graves Disease Addisons Disease
Celiac Disease Guillain Barre Syndrome

 

Note: If your research work does not match the scope of the journal please forward us your research area. The same will be forwarded to our Editorial Board and upon approval, we can add it to our scope and add the same to our list.

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